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Latest in Cardiology from ACC.org
- A-CLOSE: Clopidogrel or Extended DAPT in High Ischemic Risk?The A-CLOSE (A Randomized Comparison of CLOpidogrel Monotherapy Versus Extended Dual-antiplatelet Therapy Beyond 12 Months After Implantation of Drug-eluting StEnts in High-risk Lesions or Patients) trial compared clopidogrel monotherapy with extended dual antiplatelet therapy (DAPT) with clopidogrel plus aspirin...
- ACCEL Lite: SINGLE-AF: Anticoagulation For AFib With Intermediate Stroke RiskIn this episode, Dhanunjaya Lakkireddy MBBS, FACC and Boyoung Joung, MD discuss SINGLE-AF: Anticoagulation for atrial fibrillation with intermediate stroke risk.
- TomorrowLAND: Does Intracoronary Nicorandil Prevent No-Reflow in STEMI Patients Undergoing PCI?Prolonged perfusion balloon predilation and intracoronary delivery of Nicorandil with the Rx Ryusei perfusion balloon did not significantly reduce slow-flow or no-reflow in patients presenting with STEMI undergoing primary PCI, according to findings from the TomorrowLAND trial presented at TCT 2026.
- LIPSIA-STRATEGY: Angiography-Derived vs. Wire-Based FFR to Guide RevascularizationAngiography-derived vessel fractional flow reserve (vFFR)-guided revascularization met the prespecified absolute criterion for noninferiority to wire-based FFR, according to results from the LIPSIA-STRATEGY trial presented at TCT 2026 and simultaneously published in JACC.
- SIRONA: Sirolimus- vs. Paclitaxel-Coated Balloon Angioplasty at 3 YearsComparing sirolimus-coated balloon (SCB) and paclitaxel-coated balloon (PCB) angioplasty in patients with symptomatic femoropopliteal artery disease, no differences in walking capacity and health-related quality of life were noted; however, freedom from clinically driven target-lesion revascularization (TLR) was higher in the SCB group, according to three-year results from the SIRONA trial, presented at TCT 2026 and […]



